The LSU Peripheral Neuropathy Studies

Physical Activity for Health and Wellness for

People with Peripheral Neuropathy

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  1. A related paragraph from the 108 Congress report – Senate Appropriations Committee
  2. National Institute of Health Peripheral Neuropathy Information Page

1. A related paragraph from the 108th Congress report – Senate Appropriations Committee:

 Peripheral Neuropathy- The Committee is aware that an estimated 20 million Americans suffer from peripheral neuropathy, a neurological disorder that causes debilitating pain, weakness in the arms and legs, and difficulty walking. Peripheral neuropathy affects approximately one-third of diabetics, or about 5.1 million persons. Other forms of neuropathy are inherited; associated with cancer, kidney disease or infections like hepatitis, HIV/AIDS or Lyme disease; or caused by autoimmunity, traumatic injuries, poor nutrition, toxins and certain medications. For most of its victims, the only recourse is pain medication, physical therapy or assistive devices to help maintain strength and improve mobility. In light of the large number of individuals affected, and the attendant costs of this disease to society, the Committee is concerned that insufficient resources are being devoted to finding ways to cure, prevent and more effectively treat peripheral neuropathy. To that end, the Committee strongly urges NINDS to (1) determine how much NIH is devoting to research in this area, and (2) develop a research agenda that is coordinated with work being done through other institutes. The Committee expects to receive a report on this effort at next year's hearings.

http://thomas.loc.gov/cgi-bin/cpquery/T?&report=sr345&dbname=108&

(accessed March15, 2006)

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2. National Institute of Health Peripheral Neuropathy Information Page:

What is Peripheral Neuropathy?

Peripheral neuropathy describes damage to the peripheral nervous system, which transmits information from the brain and spinal cord to every other part of the body.

More than 100 types of peripheral neuropathy have been identified, each with its own characteristic set of symptoms, pattern of development, and prognosis. Impaired function and symptoms depend on the type of nerves -- motor, sensory, or autonomic -- that are damaged. Some people may experience temporary numbness, tingling, and pricking sensations, sensitivity to touch, or muscle weakness. Others may suffer more extreme symptoms, including burning pain (especially at night), muscle wasting, paralysis, or organ or gland dysfunction. Peripheral neuropathy may be either inherited or acquired. Causes of acquired peripheral neuropathy include physical injury (trauma) to a nerve, tumors, toxins, autoimmune responses, nutritional deficiencies, alcoholism, and vascular and metabolic disorders. Acquired peripheral neuropathies are caused by systemic disease, trauma from external agents, or infections or autoimmune disorders affecting nerve tissue. Inherited forms of peripheral neuropathy are caused by inborn mistakes in the genetic code or by new genetic mutations.

Is there any treatment?

No medical treatments exist that can cure inherited peripheral neuropathy. However, there are therapies for many other forms.  In general, adopting healthy habits -- such as maintaining optimal weight, avoiding exposure to toxins, following a physician-supervised exercise program, eating a balanced diet, correcting vitamin deficiencies, and limiting or avoiding alcohol consumption -- can reduce the physical and emotional effects of peripheral neuropathy.  Systemic diseases frequently require more complex treatments.

What is the prognosis?

In acute neuropathies, such as Guillain-Barré syndrome, symptoms appear suddenly, progress rapidly, and resolve slowly as damaged nerves heal. In chronic forms, symptoms begin subtly and progress slowly. Some people may have periods of relief followed by relapse. Others may reach a plateau stage where symptoms stay the same for many months or years. Some chronic neuropathies worsen over time, but very few forms prove fatal unless complicated by other diseases. Occasionally the neuropathy is a symptom of another disorder.

 http://www.ninds.nih.gov/disorders/peripheralneuropathy/peripheralneuropathy.htm

(accessed March 15, 2006)

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Disclaimer: The statements and opinions included in the LSU Peripheral Neuropathy Studies pages are those of Peripheral Neuropathy Studies only. Any statements and opinions included in these pages are not those of the Department of Kinesiology or the Louisiana State University or the LSU Board of Supervisors.